Direct AUC optimization of regulatory motifs

MOTIVATION: The discovery of transcription factor binding site (TFBS) motifs is essential for untangling the complex mechanism of genetic variation under different developmental and environmental conditions. Among the huge amount of computational approaches for de novo identification of TFBS motifs,...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Bioinformatics
Main Authors: Zhu, Lin, Zhang, Hong-Bo, Huang, De-Shuang
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Ismb/Eccb 2017: The 25th Annual Conference Intelligent Systems for Molecular Biology Held Jointly with the 16th Annual European Conference on Computational Biology, Prague, Czech Republic, July 21–25, 2017
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870558/
https://ncbi.nlm.nih.gov/pubmed/28881989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx255
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