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Design of potent inhibitors of HIV-1 entry from the gp41 N-peptide region

The HIV-1 gp41 envelope glycoprotein promotes fusion of the virus and cell membranes through the formation of a trimer-of-hairpins structure, in which the amino- and carboxyl-terminal regions of the gp41 ectodomain are brought together. Synthetic peptides derived from these two regions (called N and...

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Autors principals: Eckert, Debra M., Kim, Peter S.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC58705/
https://ncbi.nlm.nih.gov/pubmed/11572974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.201392898
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