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Modulating PD-L1 expression in multiple myeloma: an alternative strategy to target the PD-1/PD-L1 pathway

Even with recent advances in therapy regimen, multiple myeloma patients commonly develop drug resistance and relapse. The relevance of targeting the PD-1/PD-L1 axis has been demonstrated in pre-clinical models. Monotherapy with PD-1 inhibitors produced disappointing results, but combinations with ot...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Tremblay-LeMay, Rosemarie, Rastgoo, Nasrin, Chang, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870495/
https://ncbi.nlm.nih.gov/pubmed/29580288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-018-0589-1
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