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EZH2 as a therapeutic target for multiple myeloma and other haematological malignancies

Enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase that is of great interest in human cancer. It has been shown to have a dual nature, as it can act as a gene repressor or activator. Studies have highlighted the various roles of EZH2 in the pathophysiology of multiple myeloma (MM). It...

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Dades bibliogràfiques
Publicat a:Biomark Res
Autors principals: Tremblay-LeMay, Rosemarie, Rastgoo, Nasrin, Pourabdollah, Maryam, Chang, Hong
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286605/
https://ncbi.nlm.nih.gov/pubmed/30555699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40364-018-0148-5
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