Beta-globin gene haplotypes and selected Malaria-associated variants among black Southern African populations

Partial carrier-resistance to Plasmodium falciparum malaria conferred by the sickle cell (HbS) mutation has resulted in the local amplification and positive selection of sickle cell disease (SCD) in malaria-endemic regions and particularly in sub-Saharan Africa (SSA). The present study investigated...

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Detalhes bibliográficos
Publicado no:Glob Health Epidemiol Genom
Main Authors: Pule, G. D., Chimusa, E. R., Mnika, K., Mhandire, K., Kampira, E., Dandara, C., Wonkam, A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cambridge University Press 2017
Assuntos:
Original Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870409/
https://ncbi.nlm.nih.gov/pubmed/29868223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/gheg.2017.14
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