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Definition of EGF-like, closely interacting modules that bear activation epitopes in integrin β subunits

Integrin β subunits contain four cysteine-rich repeats in a long extracellular stalk that connects the headpiece to the membrane. Most mAbs to integrin activation epitopes map to these repeats, and they are important in propagating conformational signals from the membrane/cytosol to the ligand-bindi...

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Detalhes bibliográficos
Main Authors: Takagi, Junichi, Beglova, Natalia, Yalamanchili, Padmaja, Blacklow, Stephen C., Springer, Timothy A.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC58703/
https://ncbi.nlm.nih.gov/pubmed/11572973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.201420198
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