Definition of EGF-like, closely interacting modules that bear activation epitopes in integrin β subunits

Integrin β subunits contain four cysteine-rich repeats in a long extracellular stalk that connects the headpiece to the membrane. Most mAbs to integrin activation epitopes map to these repeats, and they are important in propagating conformational signals from the membrane/cytosol to the ligand-bindi...

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Bibliografiske detaljer
Main Authors: Takagi, Junichi, Beglova, Natalia, Yalamanchili, Padmaja, Blacklow, Stephen C., Springer, Timothy A.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2001
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC58703/
https://ncbi.nlm.nih.gov/pubmed/11572973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.201420198
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