Definition of EGF-like, closely interacting modules that bear activation epitopes in integrin β subunits

Integrin β subunits contain four cysteine-rich repeats in a long extracellular stalk that connects the headpiece to the membrane. Most mAbs to integrin activation epitopes map to these repeats, and they are important in propagating conformational signals from the membrane/cytosol to the ligand-bindi...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Takagi, Junichi, Beglova, Natalia, Yalamanchili, Padmaja, Blacklow, Stephen C., Springer, Timothy A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC58703/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11572973/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.201420198
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