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A method combining a random forest-based technique with the modeling of linkage disequilibrium through latent variables, to run multilocus genome-wide association studies
BACKGROUND: Genome-wide association studies (GWASs) have been widely used to discover the genetic basis of complex phenotypes. However, standard single-SNP GWASs suffer from lack of power. In particular, they do not directly account for linkage disequilibrium, that is the dependences between SNPs (S...
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| 出版年: | BMC Bioinformatics |
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| 第一著者: | |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5870262/ https://ncbi.nlm.nih.gov/pubmed/29587628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2054-0 |
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