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Adverse outcome pathways: Application to enhance mechanistic understanding of neurotoxicity

Recent developments have prompted the transition of empirically based testing of late stage toxicity in animals for a range of different endpoints including neurotoxicity to more efficient and predictive mechanistically based approaches with greater emphasis on measurable key events early in the pro...

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Detalhes bibliográficos
Publicado no:Pharmacol Ther
Main Authors: Bal-Price, Anna, Meek, M.E. (Bette)
Formato: Artigo
Idioma:Inglês
Publicado em: Pergamon Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869951/
https://ncbi.nlm.nih.gov/pubmed/28529068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2017.05.006
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