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Developing and applying the adverse outcome pathway concept for understanding and predicting neurotoxicity
The Adverse Outcome Pathway (AOP) concept has recently been proposed to support a paradigm shift in regulatory toxicology testing and risk assessment. This concept is similar to the Mode of Action (MOA), in that it describes a sequence of measurable key events triggered by a molecular initiating eve...
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| Publié dans: | Neurotoxicology |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5114159/ https://ncbi.nlm.nih.gov/pubmed/27212452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2016.05.010 |
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