Developing and applying the adverse outcome pathway concept for understanding and predicting neurotoxicity

The Adverse Outcome Pathway (AOP) concept has recently been proposed to support a paradigm shift in regulatory toxicology testing and risk assessment. This concept is similar to the Mode of Action (MOA), in that it describes a sequence of measurable key events triggered by a molecular initiating eve...

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Detalhes bibliográficos
Publicado no:Neurotoxicology
Main Authors: Bal-Price, Anna, Lein, Pamela J., Keil, Kimberly P., Sethi, Sunjay, Shafer, Timothy, Barenys, Marta, Fritsche, Ellen, Sachana, Magdalini, Meek, M.E. (Bette)
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114159/
https://ncbi.nlm.nih.gov/pubmed/27212452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2016.05.010
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