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Topological estimation of signal flow in complex signaling networks

In a cell, any information about extra- or intra-cellular changes is transferred and processed through a signaling network and dysregulation of signal flow often leads to disease such as cancer. So, understanding of signal flow in the signaling network is critical to identify drug targets. Owing to...

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Publicat a:Sci Rep
Autors principals: Lee, Daewon, Cho, Kwang-Hyun
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869720/
https://ncbi.nlm.nih.gov/pubmed/29588498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23643-5
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