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Topological estimation of signal flow in complex signaling networks

In a cell, any information about extra- or intra-cellular changes is transferred and processed through a signaling network and dysregulation of signal flow often leads to disease such as cancer. So, understanding of signal flow in the signaling network is critical to identify drug targets. Owing to...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lee, Daewon, Cho, Kwang-Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869720/
https://ncbi.nlm.nih.gov/pubmed/29588498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23643-5
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