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Identification of molecular interactions between P-site tRNA and the ribosome essential for translocation

Translocation of the tRNA–mRNA complex is a fundamental step in the elongation cycle of protein synthesis. Our studies show that the ribosome can translocate a P-site-bound tRNA(Met) with a break in the phosphodiester backbone between positions 56 and 57 in the TΨC-loop. We have used this fragmented...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Feinberg, Jason S., Joseph, Simpson
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC58693/
https://ncbi.nlm.nih.gov/pubmed/11562497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.211184098
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