mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding
Although the elongating ribosome is an efficient helicase, certain mRNA stem-loop structures are known to impede ribosome movement along mRNA and stimulate programmed ribosome frameshifting via mechanisms that are not well understood. Using biochemical and single-molecule Förster resonance energy tr...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications Ltd
2020-05-01
|
| Schriftenreihe: | eLife |
| Schlagworte: | |
| Online-Zugang: | https://elifesciences.org/articles/55799 |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|