mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding
Although the elongating ribosome is an efficient helicase, certain mRNA stem-loop structures are known to impede ribosome movement along mRNA and stimulate programmed ribosome frameshifting via mechanisms that are not well understood. Using biochemical and single-molecule Förster resonance energy tr...
שמור ב:
| Principais autores: | , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
eLife Sciences Publications Ltd
2020-05-01
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| סדרה: | eLife |
| נושאים: | |
| גישה מקוונת: | https://elifesciences.org/articles/55799 |
| תגים: |
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