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Type I interferon receptor knockout mice as models for infection of highly pathogenic viruses with outbreak potential

Due to their inability to generate a complete immune response, mice knockout for type I interferon (IFN) receptors (Ifnar(–/–)) are more susceptible to viral infections, and are thus commonly used for pathogenesis studies. This mouse model has been used to study many diseases caused by highly pathog...

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Detalhes bibliográficos
Publicado no:Zool Res
Main Authors: Wong, Gary, Qiu, Xiang-Guo
Formato: Artigo
Idioma:Inglês
Publicado em: Science Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869239/
https://ncbi.nlm.nih.gov/pubmed/29511140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.24272/j.issn.2095-8137.2017.052
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