Neurexin and Neuroligin-based adhesion complexes drive axonal arborisation growth independent of synaptic activity

Building arborisations of the right size and shape is fundamental for neural network function. Live imaging in vertebrate brains strongly suggests that nascent synapses are critical for branch growth during development. The molecular mechanisms underlying this are largely unknown. Here we present a...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Constance, William D, Mukherjee, Amrita, Fisher, Yvette E, Pop, Sinziana, Blanc, Eric, Toyama, Yusuke, Williams, Darren W
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869020/
https://ncbi.nlm.nih.gov/pubmed/29504935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31659
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