Regulation of RUNX1 dosage is crucial for efficient blood formation from hemogenic endothelium

During ontogeny, hematopoietic stem and progenitor cells arise from hemogenic endothelium through an endothelial-to-hematopoietic transition that is strictly dependent on the transcription factor RUNX1. Although it is well established that RUNX1 is essential for the onset of hematopoiesis, little is...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Development
Main Authors: Lie-A-Ling, Michael, Marinopoulou, Elli, Lilly, Andrew J., Challinor, Mairi, Patel, Rahima, Lancrin, Christophe, Kouskoff, Valerie, Lacaud, Georges
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2018
Fag:
Stem Cells and Regeneration
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868988/
https://ncbi.nlm.nih.gov/pubmed/29530939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.149419
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker