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Regulation of RUNX1 dosage is crucial for efficient blood formation from hemogenic endothelium
During ontogeny, hematopoietic stem and progenitor cells arise from hemogenic endothelium through an endothelial-to-hematopoietic transition that is strictly dependent on the transcription factor RUNX1. Although it is well established that RUNX1 is essential for the onset of hematopoiesis, little is...
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| Publicado no: | Development |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5868988/ https://ncbi.nlm.nih.gov/pubmed/29530939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.149419 |
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