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Characterization of a novel RP2–OSTF1 interaction and its implication for actin remodelling

Retinitis pigmentosa 2 (RP2) is the causative gene for a form of X-linked retinal degeneration. RP2 was previously shown to have GTPase-activating protein (GAP) activity towards the small GTPase ARL3 via its N-terminus, but the function of the C-terminus remains elusive. Here, we report a novel inte...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Lyraki, Rodanthi, Lokaj, Mandy, Soares, Dinesh C., Little, Abigail, Vermeren, Matthieu, Marsh, Joseph A., Wittinghofer, Alfred, Hurd, Toby
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868953/
https://ncbi.nlm.nih.gov/pubmed/29361551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.211748
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