Oxidative stress and protein damage responses mediate artemisinin resistance in malaria parasites

Due to their remarkable parasitocidal activity, artemisinins represent the key components of first-line therapies against Plasmodium falciparum malaria. However, the decline in efficacy of artemisinin-based drugs jeopardizes global efforts to control and ultimately eradicate the disease. To better u...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Pathog
Prif Awduron: Rocamora, Frances, Zhu, Lei, Liong, Kek Yee, Dondorp, Arjen, Miotto, Olivo, Mok, Sachel, Bozdech, Zbynek
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2018
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868857/
https://ncbi.nlm.nih.gov/pubmed/29538461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006930
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