Structural polymorphism in the promoter of pfmrp2 confers Plasmodium falciparum tolerance to quinoline drugs

Drug resistance in Plasmodium falciparum remains a challenge for the malaria eradication programmes around the world. With the emergence of artemisinin resistance, the efficacy of the partner drugs in the artemisinin combination therapies (ACT) that include quinoline-based drugs is becoming critical...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Microbiol
Hauptverfasser: Mok, Sachel, Liong, Kek-Yee, Lim, Eng-How, Huang, Ximei, Zhu, Lei, Preiser, Peter Rainer, Bozdech, Zbynek
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2014
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4286016/
https://ncbi.nlm.nih.gov/pubmed/24372851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12505
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