Zinc induces a Src family kinase-mediated up-regulation of NMDA receptor activity and excitotoxicity

Zinc is coreleased with glutamate from excitatory nerve terminals throughout the central nervous system and acutely inhibits N-methyl-d-aspartate (NMDA) receptor activation. Here we report that cultured murine cortical neurons briefly exposed to sublethal concentrations of zinc developed increased i...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Manzerra, Pat, Behrens, M. Margarita, Canzoniero, Lorella M. T., Wang, Xue Qing, Heidinger, Valérie, Ichinose, Tomomi, Yu, Shan Ping, Choi, Dennis W.
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 2001
Assuntos:	Colloquium Paper
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC58682/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11572968/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.191353598
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