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Inhibition of PI3K/AKT Signaling Pathway Radiosensitizes Pancreatic Cancer Cells with ARID1A Deficiency in Vitro

Pancreatic cancer is among the most aggressive human cancers, and is resistant to regular chemotherapy and radiotherapy. The AT-rich interactive domain containing protein 1A (ARID1A) gene, a crucial chromatin remodeling gene, mutates frequently in a broad spectrum of cancers, including pancreatic ca...

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Bibliografske podrobnosti
izdano v:J Cancer
Main Authors: Yang, Lin, Yang, Guanghai, Ding, Yingjun, Dai, Yuhong, Xu, Sanpeng, Guo, Qiuyun, Xie, Aini, Hu, Guangyuan
Format: Artigo
Jezik:Inglês
Izdano: Ivyspring International Publisher 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868153/
https://ncbi.nlm.nih.gov/pubmed/29581767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.21306
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