MiR-215-5p is a tumor suppressor in colorectal cancer targeting EGFR ligand epiregulin and its transcriptional inducer HOXB9

Growing evidence suggests that microRNAs are involved in the development and progression of colorectal cancer (CRC). In the present study, deregulation and functioning of tumor-suppressive miR-215-5p was evaluated in CRC. In total, 448 tumor tissues and 325 paired adjacent healthy tissues collected...

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Udgivet i:Oncogenesis
Main Authors: Vychytilova-Faltejskova, Petra, Merhautova, Jana, Machackova, Tana, Gutierrez-Garcia, Irene, Garcia-Solano, José, Radova, Lenka, Brchnelova, Dominika, Slaba, Katerina, Svoboda, Marek, Halamkova, Jana, Demlova, Regina, Kiss, Igor, Vyzula, Rostislav, Conesa-Zamora, Pablo, Slaby, Ondrej
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868056/
https://ncbi.nlm.nih.gov/pubmed/29199273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-017-0006-6
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