MiR-215-5p is a tumor suppressor in colorectal cancer targeting EGFR ligand epiregulin and its transcriptional inducer HOXB9

Growing evidence suggests that microRNAs are involved in the development and progression of colorectal cancer (CRC). In the present study, deregulation and functioning of tumor-suppressive miR-215-5p was evaluated in CRC. In total, 448 tumor tissues and 325 paired adjacent healthy tissues collected...

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Pubblicato in:Oncogenesis
Autori principali: Vychytilova-Faltejskova, Petra, Merhautova, Jana, Machackova, Tana, Gutierrez-Garcia, Irene, Garcia-Solano, José, Radova, Lenka, Brchnelova, Dominika, Slaba, Katerina, Svoboda, Marek, Halamkova, Jana, Demlova, Regina, Kiss, Igor, Vyzula, Rostislav, Conesa-Zamora, Pablo, Slaby, Ondrej
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868056/
https://ncbi.nlm.nih.gov/pubmed/29199273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-017-0006-6
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