MiR-215-5p is a tumor suppressor in colorectal cancer targeting EGFR ligand epiregulin and its transcriptional inducer HOXB9

Growing evidence suggests that microRNAs are involved in the development and progression of colorectal cancer (CRC). In the present study, deregulation and functioning of tumor-suppressive miR-215-5p was evaluated in CRC. In total, 448 tumor tissues and 325 paired adjacent healthy tissues collected...

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Vydáno v:Oncogenesis
Hlavní autoři: Vychytilova-Faltejskova, Petra, Merhautova, Jana, Machackova, Tana, Gutierrez-Garcia, Irene, Garcia-Solano, José, Radova, Lenka, Brchnelova, Dominika, Slaba, Katerina, Svoboda, Marek, Halamkova, Jana, Demlova, Regina, Kiss, Igor, Vyzula, Rostislav, Conesa-Zamora, Pablo, Slaby, Ondrej
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868056/
https://ncbi.nlm.nih.gov/pubmed/29199273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-017-0006-6
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