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Conformational Ensembles of Calmodulin Revealed by Nonperturbing Site-Specific Vibrational Probe Groups

[Image: see text] Seven native residues on the regulatory protein calmodulin, including three key methionine residues, were replaced (one by one) by the vibrational probe amino acid cyanylated cysteine, which has a unique CN stretching vibration that reports on its local environment. Almost no pertu...

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Publicat a:J Phys Chem A
Autors principals: Kelly, Kristen L., Dalton, Shannon R., Wai, Rebecca B., Ramchandani, Kanika, Xu, Rosalind J., Linse, Sara, Londergan, Casey H.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2018
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5867645/
https://ncbi.nlm.nih.gov/pubmed/29400461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpca.8b00475
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