Skeletal Muscle Pyruvate Dehydrogenase Phosphorylation and Lactate Accumulation During Sprint Exercise in Normoxia and Severe Acute Hypoxia: Effects of Antioxidants

Compared to normoxia, during sprint exercise in severe acute hypoxia the glycolytic rate is increased leading to greater lactate accumulation, acidification, and oxidative stress. To determine the role played by pyruvate dehydrogenase (PDH) activation and reactive nitrogen and oxygen species (RNOS)...

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Vydáno v:Front Physiol
Hlavní autoři: Morales-Alamo, David, Guerra, Borja, Santana, Alfredo, Martin-Rincon, Marcos, Gelabert-Rebato, Miriam, Dorado, Cecilia, Calbet, José A. L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Physiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5867337/
https://ncbi.nlm.nih.gov/pubmed/29615918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00188
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