Skeletal Muscle Pyruvate Dehydrogenase Phosphorylation and Lactate Accumulation During Sprint Exercise in Normoxia and Severe Acute Hypoxia: Effects of Antioxidants

Compared to normoxia, during sprint exercise in severe acute hypoxia the glycolytic rate is increased leading to greater lactate accumulation, acidification, and oxidative stress. To determine the role played by pyruvate dehydrogenase (PDH) activation and reactive nitrogen and oxygen species (RNOS)...

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Bibliografische gegevens
Gepubliceerd in:Front Physiol
Hoofdauteurs: Morales-Alamo, David, Guerra, Borja, Santana, Alfredo, Martin-Rincon, Marcos, Gelabert-Rebato, Miriam, Dorado, Cecilia, Calbet, José A. L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2018
Onderwerpen:
Physiology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5867337/
https://ncbi.nlm.nih.gov/pubmed/29615918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00188
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