Skeletal Muscle Pyruvate Dehydrogenase Phosphorylation and Lactate Accumulation During Sprint Exercise in Normoxia and Severe Acute Hypoxia: Effects of Antioxidants

Compared to normoxia, during sprint exercise in severe acute hypoxia the glycolytic rate is increased leading to greater lactate accumulation, acidification, and oxidative stress. To determine the role played by pyruvate dehydrogenase (PDH) activation and reactive nitrogen and oxygen species (RNOS)...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Morales-Alamo, David, Guerra, Borja, Santana, Alfredo, Martin-Rincon, Marcos, Gelabert-Rebato, Miriam, Dorado, Cecilia, Calbet, José A. L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5867337/
https://ncbi.nlm.nih.gov/pubmed/29615918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00188
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