Caricamento...

Catalpol Inhibits Amyloid-β Generation Through Promoting α-Cleavage of APP in Swedish Mutant APP Overexpressed N2a Cells

Amyloid-β (Aβ) peptides play a crucial role in the pathogenesis of Alzheimer’s disease (AD), due to its neurotoxicity. Thus, blocking Aβ generation and aggregation in the brain has been realized as an efficient way for the prevention of AD. The natural product catalpol, isolated from Rehmannia gluti...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Front Aging Neurosci
Autori principali: Wang, Zhuo, Huang, Xueshi, Zhao, Pu, Zhao, Limei, Wang, Zhan-You
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5867310/
https://ncbi.nlm.nih.gov/pubmed/29615891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00066
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !