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Inducibly decreased MITF levels do not affect proliferation and phenotype switching but reduce differentiation of melanoma cells

Melanoma arises from neural crest‐derived melanocytes which reside mostly in the skin in an adult organism. Epithelial–mesenchymal transition (EMT) is a tumorigenic programme through which cells acquire mesenchymal, more pro‐oncogenic phenotype. The reversible phenotype switching is an event still n...

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Bibliografski detalji
Izdano u:J Cell Mol Med
Glavni autori: Vlčková, Kateřina, Vachtenheim, Jiri, Réda, Jiri, Horák, Pavel, Ondrušová, Lubica
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5867098/
https://ncbi.nlm.nih.gov/pubmed/29369499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13506
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