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Inducibly decreased MITF levels do not affect proliferation and phenotype switching but reduce differentiation of melanoma cells

Melanoma arises from neural crest‐derived melanocytes which reside mostly in the skin in an adult organism. Epithelial–mesenchymal transition (EMT) is a tumorigenic programme through which cells acquire mesenchymal, more pro‐oncogenic phenotype. The reversible phenotype switching is an event still n...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Vlčková, Kateřina, Vachtenheim, Jiri, Réda, Jiri, Horák, Pavel, Ondrušová, Lubica
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5867098/
https://ncbi.nlm.nih.gov/pubmed/29369499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13506
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