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PARP1 protects from benzo[a]pyrene diol epoxide-induced replication stress and mutagenicity
Poly(ADP-ribosyl)ation (PARylation) is a complex and reversible posttranslational modification catalyzed by poly(ADP-ribose)polymerases (PARPs), which orchestrates protein function and subcellular localization. The function of PARP1 in genotoxic stress response upon induction of oxidative DNA lesion...
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| Publicat a: | Arch Toxicol |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer Berlin Heidelberg
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5866831/ https://ncbi.nlm.nih.gov/pubmed/29196784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-017-2115-6 |
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