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PARP1 protects from benzo[a]pyrene diol epoxide-induced replication stress and mutagenicity
Poly(ADP-ribosyl)ation (PARylation) is a complex and reversible posttranslational modification catalyzed by poly(ADP-ribose)polymerases (PARPs), which orchestrates protein function and subcellular localization. The function of PARP1 in genotoxic stress response upon induction of oxidative DNA lesion...
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| 發表在: | Arch Toxicol |
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| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Springer Berlin Heidelberg
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5866831/ https://ncbi.nlm.nih.gov/pubmed/29196784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-017-2115-6 |
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