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Interaction of poly-l-lysine coating and heparan sulfate proteoglycan on magnetic nanoparticle uptake by tumor cells

BACKGROUND: Poly-l-lysine (PLL) enhances nanoparticle (NP) uptake, but the molecular mechanism remains unresolved. We asked whether PLL may interact with negatively charged glycoconjugates on the cell surface and facilitate uptake of magnetic NPs (MNPs) by tumor cells. METHODS: PLL-coated MNPs (PLL-...

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Dades bibliogràfiques
Publicat a:Int J Nanomedicine
Autors principals: Siow, Wei Xiong, Chang, Yi-Ting, Babič, Michal, Lu, Yi-Ching, Horák, Daniel, Ma, Yunn-Hwa
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866726/
https://ncbi.nlm.nih.gov/pubmed/29599614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S156029
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