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Interaction of poly-l-lysine coating and heparan sulfate proteoglycan on magnetic nanoparticle uptake by tumor cells

BACKGROUND: Poly-l-lysine (PLL) enhances nanoparticle (NP) uptake, but the molecular mechanism remains unresolved. We asked whether PLL may interact with negatively charged glycoconjugates on the cell surface and facilitate uptake of magnetic NPs (MNPs) by tumor cells. METHODS: PLL-coated MNPs (PLL-...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Siow, Wei Xiong, Chang, Yi-Ting, Babič, Michal, Lu, Yi-Ching, Horák, Daniel, Ma, Yunn-Hwa
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866726/
https://ncbi.nlm.nih.gov/pubmed/29599614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S156029
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