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High resolution crystal structures of the receptor-binding domain of Clostridium botulinum neurotoxin serotypes A and FA

The binding specificity of botulinum neurotoxins (BoNTs) is primarily a consequence of their ability to bind to multiple receptors at the same time. BoNTs consist of three distinct domains, a metalloprotease light chain (LC), a translocation domain (H(N)) and a receptor-binding domain (H(C)). Here w...

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Publicat a:PeerJ
Autors principals: Davies, Jonathan R., Hackett, Gavin S., Liu, Sai Man, Acharya, K. Ravi
Format: Artigo
Idioma:Inglês
Publicat: PeerJ Inc. 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866713/
https://ncbi.nlm.nih.gov/pubmed/29576992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.4552
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