High resolution crystal structures of the receptor-binding domain of Clostridium botulinum neurotoxin serotypes A and FA

The binding specificity of botulinum neurotoxins (BoNTs) is primarily a consequence of their ability to bind to multiple receptors at the same time. BoNTs consist of three distinct domains, a metalloprotease light chain (LC), a translocation domain (H(N)) and a receptor-binding domain (H(C)). Here w...

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Bibliographic Details
Published in:PeerJ
Main Authors: Davies, Jonathan R., Hackett, Gavin S., Liu, Sai Man, Acharya, K. Ravi
Format: Artigo
Language:Inglês
Published: PeerJ Inc. 2018
Subjects:
Biochemistry
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866713/
https://ncbi.nlm.nih.gov/pubmed/29576992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.4552
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