Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay

Frontotemporal dementia (FTD) is the most common neurodegenerative disorder in individuals under age 60 and has no treatment or cure. Because many cases of FTD result from GRN nonsense mutations, an animal model for this type of mutation is highly desirable for understanding pathogenesis and testing...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Nguyen, Andrew D., Nguyen, Thi A., Zhang, Jiasheng, Devireddy, Swathi, Zhou, Ping, Karydas, Anna M., Xu, Xialian, Miller, Bruce L., Rigo, Frank, Ferguson, Shawn M., Huang, Eric J., Walther, Tobias C., Farese, Robert V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2018
Konular:
PNAS Plus
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866607/
https://ncbi.nlm.nih.gov/pubmed/29511098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1722344115
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller