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Human aging and disease: Lessons from age-related macular degeneration
Aging is the most significant risk factor associated with chronic disease in humans. The accumulation of genetic damage throughout life leads to a variety of biological aberrations, including disrupted protein homeostasis, metabolic dysfunction, and altered cellular signaling. Such changes ultimatel...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5866596/ https://ncbi.nlm.nih.gov/pubmed/29483257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1721033115 |
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