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dCas9-targeted locus-specific protein isolation method identifies histone gene regulators

Eukaryotic gene regulation is a complex process, often coordinated by the action of tens to hundreds of proteins. Although previous biochemical studies have identified many components of the basal machinery and various ancillary factors involved in gene regulation, numerous gene-specific regulators...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Tsui, Chiahao, Inouye, Carla, Levy, Michaella, Lu, Andrew, Florens, Laurence, Washburn, Michael P., Tjian, Robert
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866577/
https://ncbi.nlm.nih.gov/pubmed/29507191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1718844115
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