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Both NHERF3 and NHERF2 are necessary for multiple aspects of acute regulation of NHE3 by elevated Ca(2+), cGMP, and lysophosphatidic acid
The intestinal epithelial brush border Na(+)/H(+) exchanger NHE3 accounts for a large component of intestinal Na absorption. NHE3 is regulated during digestion by signaling complexes on its COOH terminus that include the four multi-PDZ domain-containing NHERF family proteins. All bind to NHE3 and ta...
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| Pubblicato in: | Am J Physiol Gastrointest Liver Physiol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5866371/ https://ncbi.nlm.nih.gov/pubmed/28882822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00140.2017 |
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