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Kidney Mass Reduction Leads to l‐Arginine Metabolism‐Dependent Blood Pressure Increase in Mice

BACKGROUND: Uninephrectomy (UNX) is performed for various reasons, including kidney cancer or donation. Kidneys being the main site of l‐arginine production in the body, we tested whether UNX mediated kidney mass reduction impacts l‐arginine metabolism and thereby nitric oxide production and blood p...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Pillai, Samyuktha Muralidharan, Seebeck, Petra, Fingerhut, Ralph, Huang, Ji, Ming, Xiu‐Fen, Yang, Zhihong, Verrey, François
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866334/
https://ncbi.nlm.nih.gov/pubmed/29478971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.008025
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