Kidney Mass Reduction Leads to l‐Arginine Metabolism‐Dependent Blood Pressure Increase in Mice

BACKGROUND: Uninephrectomy (UNX) is performed for various reasons, including kidney cancer or donation. Kidneys being the main site of l‐arginine production in the body, we tested whether UNX mediated kidney mass reduction impacts l‐arginine metabolism and thereby nitric oxide production and blood p...

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Veröffentlicht in:J Am Heart Assoc
Hauptverfasser: Pillai, Samyuktha Muralidharan, Seebeck, Petra, Fingerhut, Ralph, Huang, Ji, Ming, Xiu‐Fen, Yang, Zhihong, Verrey, François
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866334/
https://ncbi.nlm.nih.gov/pubmed/29478971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.008025
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