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Inhibition of Glyoxalase 1 reduces alcohol self-administration in dependent and nondependent rats

Previous studies showed that the glyoxalase 1 (Glo1) gene modulates anxiety-like behavior, seizure susceptibility, depression-like behavior, and alcohol drinking in the drinking-in-the-dark paradigm in nondependent mice. Administration of the small-molecule GLO1 inhibitor S-bromobenzylglutathione cy...

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Dades bibliogràfiques
Publicat a:Pharmacol Biochem Behav
Autors principals: de Guglielmo, Giordano, Conlisk, Dana E., Barkley-Levenson, Amanda M., Palmer, Abraham A., George, Olivier
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866249/
https://ncbi.nlm.nih.gov/pubmed/29505808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2018.03.001
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