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Drug resistance induces the upregulation of H(2)S-producing enzymes in HCT116 colon cancer cells

Hydrogen sulfide (H(2)S) production in colon cancer cells supports cellular bioenergetics and proliferation. The aim of the present study was to investigate the alterations in H(2)S homeostasis during the development of resistance to 5-fluorouracil (5-FU), a commonly used chemotherapeutic agent. A 5...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biochem Pharmacol
Prif Awduron: Untereiner, Ashley A., Pavlidou, Athanasia, Druzhyna, Nadiya, Papapetropoulos, Andreas, Hellmich, Mark R., Szabo, Csaba
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866167/
https://ncbi.nlm.nih.gov/pubmed/29061341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2017.10.007
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