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H(2)S-induced S-sulfhydration of lactate dehydrogenase A (LDHA) stimulates cellular bioenergetics in HCT116 colon cancer cells
Cystathionine-β-synthase (CBS) is upregulated and hydrogen sulfide (H(2)S) production is increased in colon cancer cells. The functional consequence of this response is stimulation of cellular bioenergetics and tumor growth and proliferation. Lactate dehydrogenase A (LDHA) is also upregulated in var...
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| Publicado no: | Biochem Pharmacol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5494970/ https://ncbi.nlm.nih.gov/pubmed/28404377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2017.03.025 |
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