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The monounsaturated fatty acid oleate is the major physiological toxic free fatty acid for human beta cells

Free fatty acids (FFAs) can cause glucose intolerance and diabetes. Lipotoxicity to the pancreatic beta cells is considered to be a major underlying cause for this phenomenon. The aim of this study was to analyse the toxicity profile of FFAs in the human EndoC-βH1 beta-cell line and to compare the r...

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Detalhes bibliográficos
Publicado no:Nutr Diabetes
Main Authors: Plötz, T, Krümmel, B, Laporte, A, Pingitore, A, Persaud, SJ, Jörns, A, Elsner, M, Mehmeti, I, Lenzen, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865546/
https://ncbi.nlm.nih.gov/pubmed/29269872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41387-017-0005-x
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