Extracellular Guanosine 5′-Triphosphate Induces Human Muscle Satellite Cells to Release Exosomes Stuffed With Guanosine

The extracellular guanosine 5′-triphosphate, GTP, has been demonstrated to be an enhancer of myogenic cell differentiation in a murine cell line, not yet in human muscle cells. Our hypothesis was that GTP could influence also human skeletal muscle regeneration, specifically in the first phases. We t...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Pietrangelo, Tiziana, Di Filippo, Ester S., Locatelli, Marcello, Piacenza, Francesco, Farina, Marco, Pavoni, Eleonora, Di Donato, Andrea, Innosa, Denise, Provinciali, Mauro, Fulle, Stefania
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865081/
https://ncbi.nlm.nih.gov/pubmed/29615899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00152
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