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Extracellular guanosine-5′-triphosphate modulates myogenesis via intermediate Ca(2+)-activated K(+) currents in C2C12 mouse cells
In this study we investigated the role of extracellular 5′-guanosine-triphosphate (GTP) on early phases of skeletal muscle differentiation using the widely used C2C12 mouse cells as a myogenic model. We show that extracellular GTP binding to specific sites activates a metabotropic cascade that leads...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1780011/ https://ncbi.nlm.nih.gov/pubmed/16455689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.102194 |
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