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Specific Inhibition of Complement Activation Significantly Ameliorates Autoimmune Blistering Disease in Mice
Epidermolysis bullosa acquisita (EBA) is an antibody-mediated blistering skin disease associated with tissue-bound and circulating autoantibodies to type VII collagen (COL7). Transfer of antibodies against COL7 into mice results in a subepidermal blistering phenotype, strictly depending on the compl...
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| Veröffentlicht in: | Front Immunol |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5865061/ https://ncbi.nlm.nih.gov/pubmed/29616034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00535 |
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